Acitretin: What It Is, How to Use It, and What to Expect

If you’ve been prescribed Acitretin, you’re probably dealing with moderate to severe plaque psoriasis or a related skin condition. It belongs to the retinoid family – drugs that are chemically similar to vitamin A. Think of it as a powerful tool that helps skin cells grow and shed at a normal rate, which can calm those stubborn plaques.

When Doctors Choose Acitretin

Doctors usually turn to Acitretin when topical creams or light therapy haven’t done the trick. It works systemically, meaning it travels through your bloodstream and reaches skin cells from the inside out. Because of that, you’ll need a prescription and regular check‑ups to make sure everything stays on track.

How to Take Acitretin Safely

Acitretin comes in tablet form, taken once daily with food. The dose starts low – often 10‑25 mg – and your doctor may increase it based on how you respond. Never double up if you miss a day; just skip the missed pill and continue as usual. Also, because Acitretin stays in your body for months, avoid pregnancy for at least three years after stopping the medication.

Blood tests are part of the routine. Your doctor will check liver function, lipids, and kidney health before you start and then every few weeks or months. If any numbers climb too high, they might lower the dose or pause treatment.

Common side effects include dry skin, chapped lips, and hair thinning. These are usually mild and improve with moisturizers or a change in dosage. More serious concerns involve elevated cholesterol or liver enzymes – that’s why those blood tests matter.

A big warning: Acitretin makes you extremely sensitive to sunlight. Pack sunscreen (SPF 30+), wear hats, and stay out of peak sun hours. Even a short outdoor walk can cause a burn if you’re not protected.

Pregnancy is non‑negotiable. Women of childbearing age must use two forms of birth control for at least one year while on Acitretin and continue until three years after the last dose. The drug can cause severe birth defects, so strict adherence to this rule saves lives.

If you notice any new symptoms – unusual bruising, joint pain, or severe headaches – call your doctor right away. These could signal rare but serious reactions.

Stopping Acitretin abruptly isn’t recommended unless instructed by a healthcare professional. Tapering off helps your body adjust and reduces the chance of flare‑ups.

Overall, Acitretin can be a game‑changer for stubborn psoriasis when used correctly. Keep open communication with your doctor, follow lab schedules, protect your skin from UV rays, and you’ll give yourself the best shot at clearer skin.